
This card is amazing for (most) Guardians, whose two primary concerns are 1. paying for their extremely expensive assets, and 2. making sure those assets actually hit when you need them.
It's useful when you have things to kill, because you can spend those dollars to boost your attacks. It's useful when you're waiting around for things to kill because it pays for fresh equipment. It's even useful when you draw two at once, because is always helpful. It's a very rare scenario where you won't get your money's worth.
The only Guardians that get nothing from it are Nate, because it doesn't work with events and doesn't really benefit Boxing Gloves for lack of a Fight action, and of course Carolyn the pacifist... with one exception.
Bruiser synergizes with Enchanted Armor. The test is a test on an Armor card, so those recurring resources can give you a +2 boost to soaking that damage. I doubt it's worthwhile for that alone, but it's a nice boost for an otherwise underwhelming card. Potentially useful for Sister Mary and Zoey Samaras if you want a more convoluted alternative to Spiritual Resolve.
[Edit:] I should probably also talk about the other classes that can take it.
Survivors tend to run a lot cheaper, so the resources aren't as much of a lifesaver. They also generally depend more on events than weapons, which it doesn't benefit. A big standout is half-Guardian William Yorick, who carries more weapons than your average survivor and tends to recur them fairly often. Those assets are cheap, but he has to pay for them each time, so it adds up.
On the Rogue front, there's of course Tony Morgan who tends to play more like a Guardian and focus less on economy than your average rogue, so a combat-boosting card that also provides econ is very welcome. Jenny Barnes is already rich, but needs a little help on the combat front due to a measley 3 , which Bruiser can provide. It helps her get out a .45 Thompson and actually hit with it, and synergizes with Mauser C96 to turn the free weapon-only dollars into actual cash to fuel the rest of her kit.